China (Mainland)
Besifloxacin HCl CAS NO.405165-61-9
- FOB Price: USD: 1.00-1.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T,MoneyGram,Other
- Available Specifications:
99%(1-5)Kilogram
- Product Details
Keywords
- 405165-61-9
- C19H21ClFN3O3.ClH
- Besifloxacin hydrochloride
Quick Details
- ProName: Besifloxacin HCl
- CasNo: 405165-61-9
- Molecular Formula: C19H21ClFN3O3.ClH
- Appearance: White powder
- Application: Pharmaceutical Intermediates
- DeliveryTime: customized
- PackAge: carton boxes or fibre drums
- Port: Chinese Main Port
- ProductionCapacity: 100 Kilogram/Month
- Purity: 99%
- Storage: Keep in cool and dry place
- Transportation: by Air or by sea
- LimitNum: 1 Kilogram
- MW: 430.305
- EINECS: 1312995-182-4
Superiority
We focus on high complex new type intermediates and fine chemical custom synthesis,scale-up production and rare chemicals. Product category including intermediates&api,catalyst and electronic chemicals.
We have our R&D team and can supply custom made service for chemicals , and keep good relationship with some pharmaceutical companies. Our synthesis level is well-known to the industry, the products are exported to US, France,Poland,Czech,Ukraine,Spain,Switzerland etc.
Our Company facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Career Chemical have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
Details
| Besifloxacin hydrochloride Basic information |
| Product Name: | Besifloxacin hydrochloride |
| Synonyms: | Besifloxacin HCl;Unii-7506A6J57t;(R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride;Besifloxacin hydrochloride;(R)-7-(3-AMinohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinolin-3-carboxylic acid HCl;3-Quinolinecarboxylic acid, 7-[(3R)-3-aMinohexahydro-1H-azepin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, Monohydrochloride (9CI);(R)-7-(3-aMinoazepan-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;7-[(3R)-3-AMinohexahydro-1H-azepin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Hydrochloride |
| CAS: | 405165-61-9 |
| MF: | C19H21ClFN3O3.ClH |
| MW: | 430.305 |
| EINECS: | 1312995-182-4 |
| Product Categories: | Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors;API |
| Mol File: | 405165-61-9.mol |
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| Besifloxacin hydrochloride Chemical Properties |
| Melting point | >210°C (dec.) |
| storage temp. | Refrigerator |
| Besifloxacin hydrochloride Usage And Synthesis |
| Outline | Besifloxacin hydrochloride is developed by Bausch & Lomba as a new type of fluoroquinolones for the treatment of bacterial conjunctivitis (a non-viral caused infectious purulent eye irritation conjunctivitis ). Bacterial conjunctivitis which is a contagious eye disease, is a common disease that affects people of all ages. The clinical symptoms of infested eye including: foreign body sensation, burning sensation, tearing; conjunctival hyperemia, mucus or purulent discharge; eyelid edema, conjunctival edema and subconjunctival hemorrhage may occur in severe cases . |
| Besifloxacin hydrochloride ophthalmic suspension |
Besifloxacin hydrochloride ophthalmic suspension (Besivance) is a fluoroquinolone drug recently approved for the topical treatment of bacterial conjunctivitis. This medicine can quickly kill common pathogens causing conjunctivitis , that is coagulase-negative staphylococci, Streptococcus pneumoniae, Staphylococcus aureus , Haemophilus influenzae bacteria, and other less common bacteria.. Besifloxacin is an effective drug to the Gram-positive and Gram-negative pathogens, include other fluoroquinolone-resistant bacteria , also it can balance the DNA gyrase and topoisomerase IV activity, slow the development of resistance. Topical administration can achieve stable and lasting high concentrations in human tears , and penetration in animal ocular tissue is good, showing excellent safety. Pharmacokinetic and pharmacodynamic characteristics of Besifloxacin meet the criteria for successfully clearing most Gram-positive and Gram-negative bacteria, while exhibiting minimal systemic exposure.Besifloxacin biochemical properties, pharmacokinetics targeted to achieve/pharmacodynamic objectives and limited to local ophthalmic drug will slow the development of bacterial resistance, making Besifloxacin become attractive choice for acute bacterial conjunctivitis treatment. The above information is edited by the chemicalbook of Tian Ye. |
| Chemical Properties | Pale Yellow Solid |
| Uses | Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic |
| Uses |
A Fluoroquinolone antibiotic. |
